We've gone through lots of different flights, to help you find the cheapest way to get from Rome Leonardo da Vinci International (Fiumicino) Airport to Santiago Chile. You can choose from five airlines. At the moment, 06 / Nov / 2025 is the cheapest date to travel, but scroll through the results to find the option that works best for you.
The most popular airlines offering flights to Santiago Chile are LATAM, KLM & Air Europa. LATAM is the most popular one, but that doesn’t mean their flights will be the cheapest. If you can't find a flight time that suits you, why not look at flying out from a different airport?
The distance between Rome Leonardo da Vinci International (Fiumicino) Airport to Santiago Chile is 11901 km. Normally, it takes about 22 hrs 25 mins to fly, and you can definitely expect the journey to be at least 18 hrs 50 mins. You can see the various flight times in the results.
If you need somewhere to stay for your trip to Chile, take a look at our accommodation options.