Cheap flights from Manchester to Des Moines

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Des Moines flight facts

What you need to know

What are the cheapest airlines?

  • American Airlines
  • United Airlines
  • Delta Air Lines

These airlines usually offer the cheapest flights from Manchester to Des Moines.

What airlines fly indirectly?

  • British Airways
  • Lufthansa
  • Air Canada

These airlines fly from Manchester to Des Moines, but you’ll have at least one layover.

How long is the flight?

13 hours 45 minutes

This is the shortest flight time from Manchester to Des Moines.

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Today alone, Netflights has searched over five flights. 05 / Feb / 2026 is currently the lowest priced day of the year to fly the Manchester/Des Moines route. There are around 35 flights on any given week from the UK to Des Moines and the cheapest month to fly right now is February. Not suitable? Try running another search or viewing all cheap flight deals.

How to get cheap flights from Manchester to Des Moines

Tips and advice from our flight experts

You've searched for flights from Manchester to Des Moines. We've found 25 flights and compared them to give you the best offers. American Airlines is the average cheapest airline for this route, so look out for them. The cheapest offer we've found is a one way ticket for the route Manchester to Des Moines on 08/04/2026 at 08:20 for £57.

We've scanned hundreds of airfares from dozens of airlines across the globe. In total, we've found 10 airlines that operate the 7,000 km flight from Manchester to Des Moines.

To find the best offers, consider booking at least 2-3 months in advance. Last-minute deals can be risky. Look for flights in the off-peak season, and check American Airlines for good rates. The average flight duration is about 13 hours 45 minutes. After selecting an offer, fill out your information and proceed to payment. Consider booking a hotel with us or use our flight + hotel service to save time and money.