Cheap flights from Manchester to Des Moines

from as little as £843

7 nights in Des Moines, departing Manchester on 23 / Apr / 2026 with Virgin Atlantic (price found 1 hour ago)

Subject to availability, prices correct of the last 24 hours
Des Moines

The Manchester / Des Moines route

All 6520 km of it

Cheap flight deals for this route

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No deals available at this time.

Des Moines flight facts

What you need to know

Alternative flights from the UK to Des Moines

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Des Moines

23 / Apr / 2026 is currently the lowest priced day of the year to fly the Manchester/Des Moines route. There are around 85 flights on any given week from the UK to Des Moines and the cheapest month to fly right now is April.

Not suitable? Try running another search or viewing all cheap flight deals.

Min / Max Temperature (°C)
LOWEST

-10 °C

AVG

10 °C

HIGHEST

30 °C

Rainfall (mm)
LOWEST

25.4 mm

AVG

76.2 mm

HIGHEST

124.5 mm

Key facts about Des Moines

How to get cheap flights from Manchester to Des Moines

Tips and advice from our flight experts

We've compared all 85 flights that go to or via Des Moines every week, to find the best deal for you. Virgin Atlantic usually has the cheapest flights from Manchester to Des Moines, so keep an eye out for them in your search results. If they’re not the cheapest option, try searching by month to compare costs throughout the week.

When you fly 6520 km from Manchester to Des Moines, you can choose from four airlines. Flights are most expensive during high season, and you can expect accommodation prices to be higher then too. Last-minute deals do crop up, but it's best to book in advance to avoid disappointment.

Virgin Atlantic, British Airways & KLM are the most popular airlines for flying from Manchester to Des Moines, so look out for their deals and offers. To find the best price, try searching by month. Or, if you want to bag a last-minute offer, keep an eye on Netflights to monitor the prices.

Flights from Manchester to Des Moines normally take 15 hrs 20 mins. Make sure you check what refreshments or meals are included, so you can plan your journey. Before you book, why not check out our holiday package and car hire options? We have some hotels close to the airport – handy if you're arriving late at night, or flying back very early.

Other popular destinations near Des Moines

Where other people are flying to

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