Your flight from Manchester to Chicago should take about 12 hrs 50 mins. We've gone through all 1,210 of the weekly flights to or via Chicago, operated by 14 airlines, to help you compare flight prices and times. At the moment, the cheapest flight is £470.
Being flexible with your dates could help you find a cheaper flight from Manchester to Chicago.
In Chicago, Chicago O'hare International Airport (ORD) is usually the cheapest airport to fly to, but there are two airports to choose from. Not sure who to fly with? Lufthansa, Virgin Atlantic & Aer Lingus are the most popular airlines available from Manchester.
If you can’t quite find what you’re looking for, try checking flight prices to other cities in the USA. Netflights has scanned 9,101 flights across the globe – and that's just today – so you're bound to find one that works for you.