Cheap flights from Manchester to Knoxville

from as little as £560

14 nights in Knoxville, departing Manchester on 07 / Oct / 2025 with Virgin Atlantic (price found 14 hours ago)

Subject to availability, prices correct of the last 24 hours
Knoxville

The Manchester / Knoxville route

All 6385 km of it

Cheap flight deals for this route

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Knoxville flight facts

What you need to know

Alternative flights from the UK to Knoxville

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Knoxville

Today alone, Netflights has searched over 215 flights. 07 / Oct / 2025 is currently the lowest priced day of the year to fly the Manchester/Knoxville route. There are around 107 flights on any given week from the UK to Knoxville and the cheapest month to fly right now is October.

Not suitable? Try running another search or viewing all cheap flight deals.

Min / Max Temperature (°C)
LOWEST

-1 °C

AVG

15 °C

HIGHEST

31 °C

Rainfall (mm)
LOWEST

70 mm

AVG

100.2 mm

HIGHEST

127 mm

Key facts about Knoxville

How to get cheap flights from Manchester to Knoxville

Tips and advice from our flight experts

We've compared all 107 flights that go to or via Knoxville every week, to find the best deal for you. Virgin Atlantic usually has the cheapest flights from Manchester to Knoxville, so keep an eye out for them in your search results. If they’re not the cheapest option, try searching by month to compare costs throughout the week.

When you fly from Manchester to Knoxville, you'll have four airlines to choose from for your 6385 km journey. If you're planning to fly in peak season, make sure you book in advance to get a reasonable price. Or you could hold on and try to get a last-minute bargain.

To sort cheap flights to Knoxville, it's best to start searching for flights by month, as this will show you when prices are at their lowest. Keep an eye on Virgin Atlantic too, as they're the most popular airline for flying from Manchester to Knoxville.

Flights from Manchester to Knoxville normally take 14 hrs 40 mins. Make sure you check what refreshments or meals are included, so you can plan your journey. Before you book, why not check out our holiday package and car hire options? We have some hotels close to the airport – handy if you're arriving late at night, or flying back very early.

Other popular destinations near Knoxville

Where other people are flying to

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