Cheap flights from Manchester to Knoxville
Cheap return flights from Manchester to Knoxville
Find the best deals
All prices shown are per person based on return flights only. Prices found in the last 48 hours.
Knoxville flight facts
What you need to know
What are the cheapest airlines?
- Spirit Airlines
- American Airlines
- Delta Air Lines
These airlines usually offer the cheapest flights from Manchester to Knoxville.
What airlines fly indirectly?
- United Airlines
- Alaska Airlines
- Southwest Airlines
These airlines fly from Manchester to Knoxville, but you’ll have at least one layover.
How long is the flight?
12 hours 30 minutes
This is the shortest flight time from Manchester to Knoxville.
Alternative flights from the UK to Knoxville
Check out prices for other routes
Alternative flights from Manchester
You might find cheaper flights nearby
Today alone, Netflights has searched over five flights. 05 / Feb / 2026 is currently the lowest priced day of the year to fly the Manchester/Knoxville route. There are around 35 flights on any given week from the UK to Knoxville and the cheapest month to fly right now is February. Not suitable? Try running another search or viewing all cheap flight deals.
How to get cheap flights from Manchester to Knoxville
Tips and advice from our flight experts
You've searched for flights from Manchester to Knoxville. We've found 15 flights and compared them to give you the best offer. Spirit Airlines is usually the cheapest for this route, so keep an eye on them. The cheapest offer we've found is a one way ticket for the route Manchester to Knoxville on 08/05/2026 at 12:30 for £59.
We've scanned hundreds of airfares from dozens of airlines across the globe. In total, we've found 8 airlines that operate the 7,200 km flight from Manchester to Knoxville.
To find the best offers, book in advance or look for last-minute deals. Consider flying with Spirit Airlines, which often has low fares. The average flight duration is about 12 hours 30 minutes. After selecting an offer, fill out your information and proceed to payment. Don't forget to check our flight + hotel service to save time and money!
Other popular destinations near Knoxville
Where other people are flying to
