We've compared all 139 flights that go to or via Knoxville every week, to find the best deal for you. Virgin Atlantic usually has the cheapest flights from Manchester to Knoxville, so keep an eye out for them in your search results. If they’re not the cheapest option, try searching by month to compare costs throughout the week.
When you fly from Manchester to Knoxville, you'll have four airlines to choose from for your 6385 km journey. If you're planning to fly in peak season, make sure you book in advance to get a reasonable price. Or you could hold on and try to get a last-minute bargain.
To sort cheap flights to Knoxville, it's best to start searching for flights by month, as this will show you when prices are at their lowest. Keep an eye on Virgin Atlantic too, as they're the most popular airline for flying from Manchester to Knoxville.
Flights from Manchester to Knoxville normally take 15 hrs 25 mins. Make sure you check what refreshments or meals are included, so you can plan your journey. Before you book, why not check out our holiday package and car hire options? We have some hotels close to the airport – handy if you're arriving late at night, or flying back very early.