Cheap flights from Manchester to Mytilene
Cheap return flights from Manchester to Mytilene
Find the best deals
All prices shown are per person based on return flights only. Prices found in the last 48 hours.
Mytilene flight facts
What you need to know
What are the cheapest airlines?
- Ryanair
- easyJet
- Jet2
These airlines usually offer the cheapest flights from Manchester to Mytilene.
What airlines fly indirectly?
- Aegean Airlines
- Lufthansa
- KLM
These airlines fly from Manchester to Mytilene, but you’ll have at least one layover.
How long is the flight?
3 hours 45 minutes
This is the shortest flight time from Manchester to Mytilene.
Alternative flights from the UK to Mytilene
Check out prices for other routes
Alternative flights from Manchester
You might find cheaper flights nearby
Today alone, Netflights has searched over five flights. 05 / Feb / 2026 is currently the lowest priced day of the year to fly the Manchester/Mytilene route. There are around 35 flights on any given week from the UK to Mytilene and the cheapest month to fly right now is February. Not suitable? Try running another search or viewing all cheap flight deals.
How to get cheap flights from Manchester to Mytilene
Tips and advice from our flight experts
You've searched for flights from Manchester to Mytilene. We've found 15 flights and compared them to give you the best offer. Ryanair is, on average, the cheapest for this route. Look out for their deals! The cheapest offer we've found is a one-way ticket for Manchester to Mytilene on 22/03/2026 at 23:45 at £42.
We've scanned hundreds of airfares from dozens of airlines across the globe. In total, we've found 5 airlines that operate the 2,800 km flight from Manchester to Mytilene.
To find the best offers, consider booking 2-3 months in advance or looking for last-minute deals. Ryanair is a popular choice for this route, with an average flight duration of 3 hours 45 minutes. After selecting an offer, fill out your information and proceed to payment. Don't forget to check our flight + hotel service to save time and money!
Other popular destinations near Mytilene
Where other people are flying to
