Cheap flights from Manchester to Santa Cruz
Cheap return flights from Manchester to Santa Cruz
Find the best deals
All prices shown are per person based on return flights only. Prices found in the last 48 hours.
Santa Cruz flight facts
What you need to know
What are the cheapest airlines?
- Ryanair
- EasyJet
- Jet2
These airlines usually offer the cheapest flights from Manchester to Santa Cruz.
What airlines fly indirectly?
- British Airways
- KLM
- Lufthansa
These airlines fly from Manchester to Santa Cruz, but you’ll have at least one layover.
How long is the flight?
12 hours 30 minutes
This is the shortest flight time from Manchester to Santa Cruz.
Alternative flights from the UK to Santa Cruz
Check out prices for other routes
Alternative flights from Manchester
You might find cheaper flights nearby
Today alone, Netflights has searched over five flights. 05 / Feb / 2026 is currently the lowest priced day of the year to fly the Manchester/Santa Cruz route. There are around 35 flights on any given week from the UK to Santa Cruz and the cheapest month to fly right now is February. Not suitable? Try running another search or viewing all cheap flight deals.
How to get cheap flights from Manchester to Santa Cruz
Tips and advice from our flight experts
You've searched for flights from Manchester to Santa Cruz. We've found 25 flights and compared various offers to give you the best deal. Ryanair is, on average, the cheapest for this route, so keep an eye on them. The cheapest offer we've found is a one-way ticket for the route Manchester to Santa Cruz on 24/05/2026 at 09:45 for £32.
We've scanned hundreds of airfares from dozens of airlines across the globe. In total, we've found 15 airlines that operate the 8,000 km flight from Manchester to Santa Cruz.
To find the best offers, book in advance or look for last-minute deals. Consider flying with Ryanair, which is popular for this route. The average flight duration is about 12 hours 30 minutes. After selecting an offer, fill out your information and payment. Don't forget to check our flight + hotel service to save time and money!
Other popular destinations near Santa Cruz
Where other people are flying to
