You’ve searched for flights from Manchester to St Louis. 70 flights go to or via St Louis every week, and we've searched them all to make it easy for you to compare your options. On average, Virgin Atlantic has the cheapest flights, so look out for them in your search results.
When you fly 6546 km from Manchester to St Louis, you can choose from four airlines. Flights are most expensive during high season, and you can expect accommodation prices to be higher then too. Last-minute deals do crop up, but it's best to book in advance to avoid disappointment.
To sort cheap flights to St Louis, it's best to start searching for flights by month, as this will show you when prices are at their lowest. Keep an eye on Virgin Atlantic too, as they're the most popular airline for flying from Manchester to St Louis.
It takes about 14 hrs to fly from Manchester to St Louis. Once you’ve chosen your flight, go through and fill out your details to complete your booking. If you haven’t yet sorted your accommodation or car hire, take a look at our competitive rates – then you can book your flights and accommodation in one go.