Cheap flights from Santo Domingo to Boston

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Boston flight facts

What you need to know

What are the cheapest airlines?

  • JetBlue Airways
  • American Airlines
  • Spirit Airlines

These airlines usually offer the cheapest flights from Santo Domingo to Boston.

What airlines fly indirectly?

  • Delta Air Lines
  • United Airlines
  • Frontier Airlines

These airlines fly from Santo Domingo to Boston, but you’ll have at least one layover.

How long is the flight?

4 hours 30 minutes

This is the shortest flight time from Santo Domingo to Boston.

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Today alone, Netflights has searched over five flights. 05 / Feb / 2026 is currently the lowest priced day of the year to fly the Santo Domingo/Boston route. There are around 35 flights on any given week from the UK to Boston and the cheapest month to fly right now is February. Not suitable? Try running another search or viewing all cheap flight deals.

How to get cheap flights from Santo Domingo to Boston

Tips and advice from our flight experts

You've searched for flights from Santo Domingo to Boston. We've found 25 flights and compared offers to give you the best deal. JetBlue Airways is, on average, the cheapest for this route. Look out for them! The cheapest offer we've found is a one-way ticket for Santo Domingo to Boston on 24/06/2026 at 16:50 at £35.

We've scanned hundreds of airfares from dozens of airlines across the globe. In total, we've found 10 airlines operating the 2,500 km flight from Santo Domingo to Boston.

To find the best offers, book in advance and consider traveling during off-peak seasons. JetBlue Airways is a popular and affordable choice for this route, with an average flight duration of 4 hours 30 minutes. After selecting an offer, fill out your information and proceed to payment. Consider booking a hotel with us or using our flight + hotel service to save time and money.