Cheap flights from Southampton to Indianapolis

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Indianapolis flight facts

What you need to know

What are the cheapest airlines?

  • American Airlines
  • Delta Air Lines
  • United Airlines

These airlines usually offer the cheapest flights from Southampton to Indianapolis.

What airlines fly indirectly?

  • British Airways
  • Lufthansa
  • Air Canada

These airlines fly from Southampton to Indianapolis, but you’ll have at least one layover.

How long is the flight?

12 hours 30 minutes

This is the shortest flight time from Southampton to Indianapolis.

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Today alone, Netflights has searched over five flights. 05 / Feb / 2026 is currently the lowest priced day of the year to fly the Southampton/Indianapolis route. There are around 35 flights on any given week from the UK to Indianapolis and the cheapest month to fly right now is February. Not suitable? Try running another search or viewing all cheap flight deals.

How to get cheap flights from Southampton to Indianapolis

Tips and advice from our flight experts

You've searched for flights from Southampton to Indianapolis. We've found 15 flights and compared them to give you the best offers. American Airlines is, on average, the cheapest for this route. Look out for them! The cheapest offer we've found is a one-way ticket for £70 from Southampton to Indianapolis on 30/04/2026 at 22:30.

We've scanned hundreds of airfares from dozens of airlines across the globe. We've found 8 airlines that operate the 7,200 km flight from Southampton to Indianapolis.

To find the best offers, consider booking 2-3 months in advance or looking for last-minute deals. Flying during off-peak seasons can also save you money. A cheap popular airline operating this route is American Airlines, with an average flight duration of 12 hours 30 minutes. After selecting an offer, fill out your information and proceed to payment. Consider booking a hotel with us or using our flight + hotel service to save time and money.