You’ve searched for flights from Southampton to San Francisco. 37 flights go to or via San Francisco every week, and we've searched them all to make it easy for you to compare your options. On average, Virgin Atlantic has the cheapest flights, so look out for them in your search results.
When you fly from Southampton to San Francisco, you'll have two airlines to choose from for your 8622 km journey. If you're planning to fly in peak season, make sure you book in advance to get a reasonable price. Or you could hold on and try to get a last-minute bargain.
If you're fairly flexible about when you want to fly to San Francisco, searching by month will show you the cheapest times to go. It’s also worth looking out for flights operated by British Airways & Virgin Atlantic, as they're the most popular airlines for this journey.
Flights from Southampton to San Francisco normally take 18 hrs 30 mins. Make sure you check what refreshments or meals are included, so you can plan your journey. Before you book, why not check out our hotel and car hire options? We have some hotels close to the airport – handy if you're arriving late at night, or flying back very early.