Cheap flights from Chicago-O'Hare to Prague
Cheap return flights from Chicago-O'Hare to Prague
Find the best deals
All prices shown are per person based on return flights only. Prices found in the last 48 hours.
Prague flight facts
What you need to know
What are the cheapest airlines?
- Ryanair
- Wizz Air
- United Airlines
These airlines usually offer the cheapest flights from Chicago-O'Hare to Prague.
What airlines fly indirectly?
- Lufthansa
- British Airways
- Air France
These airlines fly from Chicago-O'Hare to Prague, but you’ll have at least one layover.
How long is the flight?
10 hours 30 minutes
This is the shortest flight time from Chicago-O'Hare to Prague.
Alternative flights from the UK to Prague
Check out prices for other routes
Alternative flights from Chicago-O'Hare
You might find cheaper flights nearby
Today alone, Netflights has searched over five flights. 05 / Feb / 2026 is currently the lowest priced day of the year to fly the Chicago-O'Hare/Prague route. There are around 35 flights on any given week from the UK to Prague and the cheapest month to fly right now is February. Not suitable? Try running another search or viewing all cheap flight deals.
How to get cheap flights from Chicago-O'Hare to Prague
Tips and advice from our flight experts
You've searched for flights from Chicago-O'Hare to Prague. We've found 25 flights and compared them to give you the best offer. Ryanair is, on average, the cheapest for this route, so keep an eye on them. The cheapest offer we've found is a one-way ticket for the route from Chicago-O'Hare to Prague on 29/05/2026 at 14:15 for £65.
We've scanned hundreds of airfares from dozens of airlines across the globe. In total, we've found 15 airlines that operate the 7,800 km flight from Chicago-O'Hare to Prague.
To find the best offers, consider booking 2-3 months in advance or looking for last-minute deals. Ryanair is a popular and affordable option for this route, with an average flight duration of 10 hours 30 minutes. After selecting an offer, fill out your information and proceed to payment. Don't forget to check our flight + hotel service to book everything at once, saving you time and money.
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