Your flight from San Francisco to Chicago should take about 8 hrs 5 mins. We've gone through all 34 of the weekly flights to or via Chicago, operated by four airlines, to help you compare flight prices and times. At the moment, the cheapest flight is £179.
Or, if you're fairly flexible on dates, try to get a last minute-deal by regularly checking the Netflights website.
Chicago actually has two airports – but Chicago O'hare International Airport is normally the cheapest one to fly into. If you're not sure who to fly with from San Francisco, you might like to know that Delta Air Lines is the most popular airline for this route.
If you can’t find flights that suit you, consider flying to another part of the USA.
