Cheap flights from Southampton to Key West
Cheap return flights from Southampton to Key West
Find the best deals
All prices shown are per person based on return flights only. Prices found in the last 48 hours.
Key West flight facts
What you need to know
What are the cheapest airlines?
- American Airlines
- Delta Air Lines
- JetBlue Airways
These airlines usually offer the cheapest flights from Southampton to Key West.
What airlines fly indirectly?
- United Airlines
- Alaska Airlines
- Spirit Airlines
These airlines fly from Southampton to Key West, but you’ll have at least one layover.
How long is the flight?
12 hours
This is the shortest flight time from Southampton to Key West.
Alternative flights from the UK to Key West
Check out prices for other routes
Alternative flights from Southampton
You might find cheaper flights nearby
Today alone, Netflights has searched over five flights. 05 / Feb / 2026 is currently the lowest priced day of the year to fly the Southampton/Key West route. There are around 35 flights on any given week from the UK to Key West and the cheapest month to fly right now is February. Not suitable? Try running another search or viewing all cheap flight deals.
How to get cheap flights from Southampton to Key West
Tips and advice from our flight experts
You've searched for flights from Southampton to Key West. We've found 25 flights and compared them to give you the best offers. American Airlines is, on average, the cheapest for this route, so keep an eye on them. The cheapest offer we've found is a one-way ticket for £33 from Southampton to Key West on 24/05/2026 at 15:15.
We've scanned hundreds of airfares from dozens of airlines across the globe. In total, we've found 10 airlines that operate the 7,200 km flight from Southampton to Key West.
To find the best offers, consider booking 2-3 months in advance or looking for last-minute deals. Try JetBlue Airways for a budget-friendly option. The average flight duration is about 12 hours. After selecting an offer, fill out your information and payment. Consider booking a hotel with us or using our flight + hotel service to save time and money.
Other popular destinations near Key West
Where other people are flying to
